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Effects of laser on inflamatory periodontal disease(periodontitis)

Comparison of the effects of scaling and root planning with or without photodynamic therapy (with indocyanine green) and 810nm diode laser on clinical parameters and biomarkers of gingival crevicular fluid in chronic periodontitis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015060722598N1
Enrollment
14
Registered
2016-05-18
Start date
2015-11-03
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic periodotitis. Chronic periodontitis

Interventions

Intervention 1: 1-SRP alone(Control). Intervention 2: Photodynamic therapy with laser diode 810 nm. And 0/4 w and indocyaningreen + srp. Intervention 3: Laser diode810 nm and 1/5 w + srp.
Treatment - Other
Treatment - Drugs
1-SRP alone(Control).
Photodynamic therapy with laser diode 810 nm. And 0/4 w and indocyaningreen + srp
Laser diode810 nm and 1/5 w + srp

Sponsors

Shahid Beheshti Dental School
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: good general health; patient presented with chronic periodontitis as defined by periodontist; pateints must have 12 natural teeth with a minimum of three in each quadrant, teeth must have CAL>3 mm & PD>5mm with BOP. Exclusion criteria: systemic diseases including: diabetes mellitus; cancer, HIV, metabolic disorders; pregnancy & lactation; estrogen therapy for female patients; smokers; patient who had received systemic antibiotics within the past 6 months; surgical or non-surgical periodontal treatment within the past 6 months & class III mobility of tooth.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Periodontal depth-. Timepoint: Before treatment,1&3 month after treatmenr. Method of measurement: PD with periodontal probing.;Clinical attachment level. Timepoint: Before treatment,1&3 month after treatmenr. Method of measurement: cal with periodontal probing.;IL-1B. Timepoint: Before treatment,1&3 month after treatmenr. Method of measurement: ELISA test.;Bleeding on probing. Timepoint: Before treatment,1&3 month after treatmenr. Method of measurement: observation 30-60 sec after pocket probing.;IL-4. Timepoint: Before treatment,1&3 month after treatmenr. Method of measurement: ELISA test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mansour Meimandi

Shahid Beheshti Dental School

meimandim@sbum.ac.ir; parisayousefnejad@yahoo.com+98 21 2240 3075

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026