renal colic. Unspecified renal colic
Conditions
Interventions
Intervention 1: Intervention group:5 mg Morphine Sulfate along with 10 mg Chlorpheniramin ,over one hour, on minutes 00,15,30,45,60 by intravenous administration. Intervention 2: Control group:5 mg Mo
Treatment - Drugs
Intervention group:5 mg Morphine Sulfate along with 10 mg Chlorpheniramin ,over one hour, on minutes 00,15,30,45,60 by intravenous administration
Control group:5 mg Morphine Sulfate along with 10 mg Distilled water ,over one hour, on minutes 00,15,30,45,60 by intravenous administration
Sponsors
Ahvaz Jundishapur University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age range from 18 to 55 years old, clinical diagnosis of acute colic pain, pain intensity of 7-10 based on VAS, and patients’ consent for participation in the study. Exclusion criteria: Angle-closure Glaucoma, Symptomatic benign prostatic hypertrophy (BPH) - peptic ulcer disease - a bladder neck obstruction - pyloric or duodenal obstruction - Chronic obstructive pulmonary disease (COPD) - Asthma - sleep apnea - urinary retention - Hyperthyroidism - high intraocular pressure and blood pressure - cardiovascular diseases. Also, pregnancy or suspected pregnancy, contraindications for receiving morphine and citalopram according to the drugs’ catalog, a history of dependency on opioid or SSRIs, receiving an analgesic drug within last 6-hours, peritonitis or signs of peritoneal irritation, inability to communicate for any reason, patient’s withdrawal from participation in the study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain intensity. Timepoint: at base line (00), 15, 30, 45, 60 minutes of treatment. Method of measurement: observation, Using a 10-cm visual analog scale, the pain intensity will be measured. ( 10= intolerable pain, 1= no pain). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Behrad Ziapour
Ahvaz Jundishapur University of Medical Sciences
Outcome results
None listed