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The effect of selenium on preventing pregnancy induced hypertension

Comparison the efficacy of selenium on preventing preeclampsia in pregnant women

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201506034339N9
Enrollment
270
Registered
2015-08-01
Start date
2015-05-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preeclampsia. Pre-existing hypertension complicating pregnancy, childbirth and the puerperium

Interventions

Intervention 1: Pregnant women from 24 to 40 weeks of pregnancy (duration:16 weeks) will get 200 micrograms of selenium per day orally. Intervention 2: Pregnant women from 24 to 40weeks of pregnancy (
Treatment - Drugs
Pregnant women from 24 to 40 weeks of pregnancy (duration:16 weeks) will get 200 micrograms of selenium per day orally.
Pregnant women from 24 to 40weeks of pregnancy (duration: 16 weeks) based on study criteria will not get any medication.

Sponsors

Vice-chancellery for Research of Bushehr University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Singleton pregnancy; gestational age of 24 weeks; willingness to participate in the study; body mass index of 19 to 30 and at least 4 kg during the first 6 month of pregnancy weight gain as well. Exclusion criteria: Abnormal fetal ultrasound; the risk of chronic disease such as diabetes and hypertension; hypertension drugs requirement; chronic and sever illness of the kidney; adrenal, thyroid and parathyroid; cardiovascular; infection; malignancies, immune system disorders; use of alcohol and tobacco; severe stress in pregnancy period; consumption anti-cancer drugs; aspirin; anticoagulants; daily using over 60 mg of iron; daily using calcium and consumption of zinc.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Hypertension. Timepoint: 24 weeks and 32 weeks of gestational age and delivery time. Method of measurement: mmHg and with Sphygmomanometer.

Secondary

MeasureTime frame
Urine protein. Timepoint: 24wks , 32wks , delivery time. Method of measurement: urinaryanalysis.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElham Rahmani

Bushehr University of Medical Sciences

Rahmani@bpums.ac.ir+98 77 3252 2081

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026