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Effect of promipexol versus no treatment in migraine patients with restlessleg syndrome

Effect of promipexol versus no treatment in migraine patients with restlessleg syndrome: a before after clinical trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201506019014N63
Enrollment
44
Registered
2015-06-06
Start date
2014-09-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine. Migraine

Interventions

Intervention 1: In comparison with before treatment. Intervention 2: Routine treatment plus promipexol 18 mg (on fourth of tablet) once a night and then increasing the dose gradually to a maximum of o
Treatment - Drugs
Routine treatment plus promipexol 18 mg (on fourth of tablet) once a night and then increasing the dose gradually to a maximum of one tablet every night for 3 months

Sponsors

Vice-chancellor for Research the Technology, Hamadan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: (a) The frequency of headache at least 4 times a month; (b) headache leads to dysfunction. Exclusion criteria: (a) breastfeeding and pregnancy; (b) contraindication of promipexol.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Assessing the frequency of headache. Timepoint: one, two, and three months after treatment . Method of measurement: using questionnaire.

Secondary

MeasureTime frame
Assessing the dizziness. Timepoint: one, two, and three months after treatment. Method of measurement: using questionnaire.;Assessing the insomnia. Timepoint: one, two, and three months after treatment. Method of measurement: using questionnaire.;Assessing the nausea and vomiting. Timepoint: one, two, and three months after treatment. Method of measurement: using questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAfshin Afshari

Farshchian Hospital

afsharafshin68@gmail.com+98 81 3827 4184

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026