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A Comparative of high dose and low dose adrenocorticotropic hormone (ACTH) therapy for infantile spasm

A Comparative of high dose and low dose adrenocorticotropic hormone (ACTH) therapy for infantile spasm

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015060110634N2
Enrollment
30
Registered
2016-02-09
Start date
2014-03-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infantile spasm. Other generalized epilepsy and epileptic syndromes

Interventions

Intervention 1: Intervention group: ACTH injection Ampul 10 mg / 0/25 mg/ novartis products/ According to PRrotocol of study for 6 months. Intervention 2: Control group: ACTH Ampul injection 10 mg/ 0
Treatment - Drugs
Intervention group: ACTH injection Ampul 10 mg / 0/25 mg/ novartis products/ According to PRrotocol of study for 6 months.
Control group: ACTH Ampul injection 10 mg/ 0/1 mg According to Protocol of study for 6 months.

Sponsors

Vice Chancellor for research of Hamedan Univercity of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: inclusion criteria: infant with infantile spasm exclusion criteria: 1-cancel from participation in research 2-Lack of consent to start therapy

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Count of seizure. Timepoint: 6 months later intervention. Method of measurement: Clinical scale.;Hospitalization duration. Timepoint: 6 months later intervention. Method of measurement: day.;Demands of other drugs. Timepoint: 6 months later intervention. Method of measurement: Clinical scale.;Prognosis. Timepoint: 6 months afterr intervention. Method of measurement: Clinical veiw.

Secondary

MeasureTime frame
Hypoglycemia. Timepoint: 6 months after intervention. Method of measurement: glocometry.;Blood pressure. Timepoint: 6 months afterr intervention. Method of measurement: Manometr.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSamira Mokhtari

Hamedan University of Medical Sciences

s.mokhtari63@gmail.com;afshin_fay@yahoo.com+98 21 7790 9733

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026