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Comparison of herbal composition colchicum autumnale, saffon and ginger with celecoxib on clinical symptoms in aged 60-70 years with osteoarthritis of the knee in Bushehr

Comparison of herbal composition colchicum autumnale, saffon and ginger with celecoxib on clinical symptoms in aged 60-70 years with osteoarthritis of the knee in Bushehr

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015053022466N1
Enrollment
160
Registered
2015-08-05
Start date
2015-07-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoartritis. Loose body in knee

Interventions

Intervention 1: In group A, before the intervention using a questionnaire and clinical symptoms of knee osteoarthritis in the participants will check .Then initially treat with celecoxib 100 mg twice
Treatment - Drugs
In group A, before the intervention using a questionnaire and clinical symptoms of knee osteoarthritis in the participants will check .Then initially treat with celecoxib 100 mg twice a day for 2 mon
In group B, before the intervention using a questionnaire and clinical symptoms of knee osteoarthritis in the participants will check .Then initially the group B treat with herbal Capsules (colchicum

Sponsors

Bushehr University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
34 Years to 14 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria included age located within 60 to 70 years (young adult), getting older, based on clinical signs of osteoarthritis of the knee (Knee pain, stiffness and loss of function of the knee) based on the doctor, the symptoms for more than 6 months,getting treated with pain medication, avoiding the use of drugs (opium, etc.), lack of trauma to the knee, no history of hypersensitivity to NSAIDs or a history of gastrointestinal bleeding, Consent to participate in the study? Being mentally alert? ability to verbal communication? response to questions? reform of temperament by physician. exclusion criteria:lack of routine monitoring of patients taking drug? other analgesic use during the period? the patient's unwillingness to continue to participate? trauma to the knee during therapy? the patient only. , and with the ability to track enough to be conscious of the mind and the ability to communicate verbally and modified Vpaskhgvyy questions natured doctor (regimen) are. Exclusion criteria included non-routine monitoring of the patient's medications, other analgesic consumption during the period, the company's unwillingness to continue the patient and trauma to the knee during the treatment period and are just being patient.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: before and after intervention. Method of measurement: VAS and Koos questionnaire.;Knee regidity. Timepoint: before and after intervention. Method of measurement: Koss questionnaire.;Activity daily living disfunction. Timepoint: before and after intervention. Method of measurement: Koss questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahnaz Pouladi, PhD

Bushehr University of Medical Sciences

pouladi2008@yahoo.com sh.pooladi@bpums.ac.ir+98 77 3455 0187

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026