Investigation the effect of local anesthesia in nose with %0.5 tetracaine drop on blood pressure, bleeding during surgery and pain after surgery in septoplasty.

Investigation the effect of local anesthesia in nasal mucosa with %0.5 tetracaine drop on hemodynamic changes, bleeding during surgery and pain after surgery in septoplasty.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201505266252N8

Enrollment

Registered

2015-07-17

Start date

2013-12-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Septal deviation. Deviated nasal septum

Interventions

Intervention 1: In the first group, dipped cotton in 10 drops of %0.5 tetracaine is put in each nasal cavity. Intervention 2: in the second group, dipped cotton in normal saline is put in each nasal c

Treatment - Drugs

In the first group, dipped cotton in 10 drops of %0.5 tetracaine is put in each nasal cavity.

in the second group, dipped cotton in normal saline is put in each nasal cavity.

Eligibility

Sex/Gender

All

Age

15 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: The 15-35 years old patients with ASAI and II that candidate for septoplasty. Exclusion criteria: History of hypersensitivity to tetracaine or other local anesthetic drugs, history of using analgesics more than 5 days continuously in last month, history of drug abuse. weight more than 100 kg or less than 30kg, history of hypertension.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Systolic blood pressure. Timepoint: 5 minute before anesthesia, 10, 15 and 20 minute after anesthesia. Method of measurement: with manometer.;Diastolic blood presure. Timepoint: 5 minute before anesthesia, 10, 15 and 20 minute after anesthesia. Method of measurement: with manometer.;Pulse rate. Timepoint: 5 minute before anesthesia, 10, 15 and 20 minute after anesthesia. Method of measurement: with pulse oxymeter.	—

Measure

Time frame

Systolic blood pressure. Timepoint: 5 minute before anesthesia, 10, 15 and 20 minute after anesthesia. Method of measurement: with manometer.;Diastolic blood presure. Timepoint: 5 minute before anesthesia, 10, 15 and 20 minute after anesthesia. Method of measurement: with manometer.;Pulse rate. Timepoint: 5 minute before anesthesia, 10, 15 and 20 minute after anesthesia. Method of measurement: with pulse oxymeter.

—

Secondary

Measure	Time frame
Pain and restlessness. Timepoint: 10 minutes after enterance to recovery and 70 minutes after end of surgery. Method of measurement: VAS questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSoroush Amani MD

Shahrekord University of Medical Sciences

info@Skums.ac.ir+98 38 3334 9506

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026