Effect of one section strenuous physical activity & Crocus stavus Supplementation on HSP 70 , IL-6, TNF a in male mountain climbers

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015052622416N1

Enrollment

Registered

2016-08-15

Start date

2015-11-06

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Effect of one section strenuous physical activity & Crocus stavus Supplementation. Examination for normal comparison and control in clinical research programme

Interventions

Saffron supplementation

dose of 300 mg per day

once per day

for 10 days.

for 10 days

Eligibility

Sex/Gender

Male

Age

27 Years to 37 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria : with minimum 2 years mountaineering ; Climbing experience at minimum height of 4000 meter ; A minimum height of 3500 m bivouac; who were not smoking; No overweight ;No history of endocrine diseases;No diabetes;No heart disease and chronic disease exclusion criteria : Endocrine diseases ; Diabetes; Heart disease and any disease lack of taking the supplements for any reason; Failure to observe the test conditions such as altitude sports

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Hsp 70. Timepoint: Before Saffron supplementation: Before physical activity , Immediately after physical activity , 1 hour post-physical activity - After supplementation Saffron : Before physical activity , Immediately after physical activity , 1 hour after physical activity. Method of measurement: Using blood, serum Hsp70 value in Nanograms per deciliter by Kit.;IL-6. Timepoint: Before Saffron supplementation: Before physical activity , Immediately after physical activity , 1 hour post-physical activity - After supplementation Saffron : Before physical activity , Immediately after physical activity , 1 hour after physical activity. Method of measurement: Using blood, serum IL-6 value in Picograms per deciliter by Kit.;TNFa. Timepoint: Before Saffron supplementation: Before physical activity , Immediately after physical activity , 1 hour post-physical activity - After supplementation Saffron : Before physical activity , Immediately after physical activity , 1 hour after physical activity. Method of measurement: Using blood, serum TNFa value in Picograms per deciliter by Kit.	—

Measure

Time frame

Hsp 70. Timepoint: Before Saffron supplementation: Before physical activity , Immediately after physical activity , 1 hour post-physical activity - After supplementation Saffron : Before physical activity , Immediately after physical activity , 1 hour after physical activity. Method of measurement: Using blood, serum Hsp70 value in Nanograms per deciliter by Kit.;IL-6. Timepoint: Before Saffron supplementation: Before physical activity , Immediately after physical activity , 1 hour post-physical activity - After supplementation Saffron : Before physical activity , Immediately after physical activity , 1 hour after physical activity. Method of measurement: Using blood, serum IL-6 value in Picograms per deciliter by Kit.;TNFa. Timepoint: Before Saffron supplementation: Before physical activity , Immediately after physical activity , 1 hour post-physical activity - After supplementation Saffron : Before physical activity , Immediately after physical activity , 1 hour after physical activity. Method of measurement: Using blood, serum TNFa value in Picograms per deciliter by Kit.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Jan Bozorgi

Islamic Azad University, Science and Research

Fattima25jb@gmail.com+98 214486517982

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026