Female infertility. Female infertility
Conditions
Interventions
Intervention 1: Intervention group received 2 clomiphene 50 mg\day from day 3 to day 7 of menstruation and 4 mg estradiol valerate after day 3 to day 14. Intervention 2: Control group received 2 ltetr
Treatment - Drugs
Intervention group received 2 clomiphene 50 mg\day from day 3 to day 7 of menstruation and 4 mg estradiol valerate after day 3 to day 14.
Control group received 2 ltetrozol 2.5mg/day from day 3 to day 7 of menstruation, for similarity and also blindness of study, placebo was gave to this group.
Sponsors
Vice Chancellor for Research, Kurdistan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 48 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: polycystic ovary syndrome based on Rotterdam Criteria; age between 18 to 48 years old; menstrual disturbances (oligomenorrhea or amenorrhea); clinical or biochemical hyperandrogenism. Exclusion criteria: hyperprolactinemia; thyroid problems; anatomical probleb of uterin cavity and fallopian tubes which is approved by hsterosalpingography.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Endometrial thickness. Timepoint: Day 14 of the menstrual cycle. Method of measurement: Transvaginal ultrasound.;Pregnancy. Timepoint: One month after the menstrual cycle. Method of measurement: positive BHCG and ultrasound.;Abortion. Timepoint: Three months (in the case of Pregnancy). Method of measurement: The patient's medical record. | — |
Secondary
| Measure | Time frame |
|---|---|
| Endometrial thickness improvement. Timepoint: On day 14 of the menstrual cycle. Method of measurement: Transvaginal ultrasound. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactLale Tngestani
Kurdistan University of Medical Sciences
Outcome results
None listed