Survey of prescription of Azithromycin in treatment of patients with Chronic Periodontitis.

Survey of systemic prescription of Azithromycin using Salivary Occult Blood Test (SOBT) and periodontal parameters in non-surgical treatment of patients with moderate to severe Chronic Periodontitis.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015052510304N2

Enrollment

Registered

2015-06-10

Start date

2015-06-07

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Periodontitis. Chronic periodontitis

Interventions

Intervention 1: Tab Azithromycine 250 mg, 1 per day, loading dose 500 mg. Intervention 2: Tab Placebo, 1 per day, loading dose 2 tabs.

Treatment - Drugs

Placebo

Tab Placebo, 1 per day, loading dose 2 tabs

Tab Azithromycine 250 mg, 1 per day, loading dose 500 mg

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age over 18 years old; have at least 20 teeth; existence of chronic periodontitis. Exclusion criteria: antibiotics therapy during the last 3 months; a history of allergy to macrolides; smokers (more than 5 cigarettes a day); periodontal treatment during the last 3 months; systemic diseases affecting the periodontal condition such as diabetes; blood disorders and diseases of the immune system (systemic disease according to patient and medical history evaluated); patients treated with drugs Anitacid and Cyclosporine; patients with anemia (anemia according to patient and medical history estimated); patients with thrombocytopenia and liver defects; patients with leukemia; the use of aspirin and other anticoagulants; use Corticosteroids (up to one year).

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Probing Depth. Timepoint: Before Intervention And 1 Mounth After Intervention And 2 Mounth After Intervention. Method of measurement: Milimeter.;Bleeding on Probing. Timepoint: Before Intervention And 1 Mounth After Intervention And 2 Mounth After Intervention. Method of measurement: Present ( 0 - 100 ).;Gingival Recession. Timepoint: Before Intervention And 1 Mounth After Intervention And 2 Mounth After Intervention. Method of measurement: Milimeter.;Gingival Index. Timepoint: Before Intervention And 1 Mounth After Intervention And 2 Mounth After Intervention. Method of measurement: 0, 1 , 2, 3.;Clinical Aattachment Level. Timepoint: Before Intervention And 1 Mounth After Intervention And 2 Mounth After Intervention. Method of measurement: Milimeter.;Salivary Occult Blood. Timepoint: Before Intervention And 1 Mounth After Intervention And 2 Mounth After Intervention. Method of measurement: 0, 1.;Groups. Timepoint: Before Intervention And 1 Mounth After Intervention And 2 Mounth After Intervention. Method of measurement: 1, 2.	—

Measure

Time frame

Probing Depth. Timepoint: Before Intervention And 1 Mounth After Intervention And 2 Mounth After Intervention. Method of measurement: Milimeter.;Bleeding on Probing. Timepoint: Before Intervention And 1 Mounth After Intervention And 2 Mounth After Intervention. Method of measurement: Present ( 0 - 100 ).;Gingival Recession. Timepoint: Before Intervention And 1 Mounth After Intervention And 2 Mounth After Intervention. Method of measurement: Milimeter.;Gingival Index. Timepoint: Before Intervention And 1 Mounth After Intervention And 2 Mounth After Intervention. Method of measurement: 0, 1 , 2, 3.;Clinical Aattachment Level. Timepoint: Before Intervention And 1 Mounth After Intervention And 2 Mounth After Intervention. Method of measurement: Milimeter.;Salivary Occult Blood. Timepoint: Before Intervention And 1 Mounth After Intervention And 2 Mounth After Intervention. Method of measurement: 0, 1.;Groups. Timepoint: Before Intervention And 1 Mounth After Intervention And 2 Mounth After Intervention. Method of measurement: 1, 2.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Seyed Reza Arabi

Hamedan University Of Medical Sciences, Dentistry Faculty

sr.arabi@umsha.ac.irsr_arabi@yahoo.com+98 81 3838 1074

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026