Pain in extrimity fracture. Injury, poisoning and certain other consequences of external causes
Conditions
Interventions
Intervention 1: Control group will receive intravenous morphine 5 mg and placebo suppository . Intervention 2: Case group will receive 10 mg suppository morphine and 5 ml of intravenous distilled wate
Treatment - Drugs
Control group will receive intravenous morphine 5 mg and placebo suppository .
Case group will receive 10 mg suppository morphine and 5 ml of intravenous distilled water.
Sponsors
Vice Chancellor of Research of Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: trauma patients with acute extremity fracture between 18 and 70 years old who have moderate to severe pain according to their visual analogue scale (VAS) score (score equal or higher than 5 of 10) Exclusion Criteria: known opioid allergy, a history of current/past drug abuse, other concurrent causes of pain (including trauma to other site), history of any chronic diseases (like respiratory, renal, hepatic, or heart failure), any conditions impairing the patient’s cooperation and participation in study (including altered consciousness, mental disorders and language barrier), pregnant and breastfeeding women and patients who had received analgesics 24 hours before admission
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of pain. Timepoint: 0.30.60 minutes and 1,3,6,12,18,24 hour. Method of measurement: numerical criteria on the base of VAS score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Apnea,decreased Oxygen suturation, decreased level of consciousness, decreased blood pressure, nausea and vomiting. Timepoint: 0-30-60 minutes and 1,3,6,12,18,24 hour. Method of measurement: Checking the patients respiratory rate, Oxygen saturation on pulse oximetry, checking blood pressure and asking about nausea and vomiting. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHoda Taghipour
Iran University of Medical Sciences
Outcome results
None listed