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Effect of daily sedation vacation on ventilator associated pneumonia

The effect of daily sedation vacation protocol on incidence of early ventilator-associated pneumonia in mechanically ventilated patient in Alzahra hospital, Isfahan University of Medical Sciences, 2014-2015.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015052022353N1
Enrollment
80
Registered
2016-06-07
Start date
2014-08-11
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventilator Associated Pnoumonia. Unspecified acute lower respiratory infection

Interventions

Intervention 1: Protocol includes a Scale to assess the level of sedation and to evaluate the restlessness and a scale to measure patient's lung infection. To assess sedation level and the agitation w
Treatment - Drugs
Protocol includes a Scale to assess the level of sedation and to evaluate the restlessness and a scale to measure patient's lung infection. To assess sedation level and the agitation will use the RASS
For the control group, to sedation vacation, previous routine done and according the overall nurses and physicians assessment considering the drug changes.

Sponsors

Vice Chancellor for Research, Isfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Major inclusion criteria: age over than 18 and less than 65; under mechanical ventilation for at least 24 hour; have no any history of pneumonia in beginning of study; have no increased intra cranial pressure, seizure, brain stroke and Glasgow coma scale under 8; and stable hemodynamic; Major exclusion criteria: Unwillingness to stay in study; death; going to other wards or hospitals; sever agitation; surgery during study;

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Ventilator Associated Pnoumonia. Timepoint: Third and fourd and fived day after start sedation infusion. Method of measurement: By Modified Clinical Pulmonary Infection Score.

Secondary

MeasureTime frame
Intubation time. Timepoint: Third and fourd and five day after start sedation infusion. Method of measurement: Readines for patient extubation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahdi ?Shahabi

Isfahan University of Medical Science

Mshahab1363@yahoo.com+31 37927543

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026