infertility. Female infertility associated with anovulation
Conditions
Interventions
Intervention 1: 1 mg daily of placebo gel (10 mg) on the external surface of the thigh in the control group. Intervention 2: 1 mg daily testosterone gel 1% (10 mg) on the external surface of the thigh
Treatment - Drugs
1 mg daily of placebo gel (10 mg) on the external surface of the thigh in the control group
1 mg daily testosterone gel 1% (10 mg) on the external surface of the thigh in the intervention group
Sponsors
Isfahan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
30 Years to 42 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1-aged between 30 and 42 years 2-agreed to participate in the study 3- poor response to ovarian stimulation in IVF and ICSI methods previous (plasma estradiol level <1200 pg ml daily on HCG, the number of oocytes <5) 4- evidence of decreased ovarian reserve (which Drsvmyn day menstrual cycle, according to an abnormally low level of estradiol, inhibin B, and FSH defined) 5- no history of ovarian surgery, endometriosis, metabolic disorders and cancer Brest Exclusion criteria: 1- not referring patients to determine the level of hormones in ovarian reserves 2- lack of testosterone gel completely or irregular use it to continue the development of allergies or severe medical complications of drug use is prohibited. 3-Pregnancy
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ovarian reserve hormones ( FSH-LH-Progestrone-E2). Timepoint: end of each cycle. Method of measurement: laboratory assessment.;Antral follicles numbers. Timepoint: end of each cycle. Method of measurement: sonography.;Antral follicles size. Timepoint: end of each cycle. Method of measurement: sonography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactatena khayambashi
medical science school
Outcome results
None listed