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Calcitriol and cholecalciferol effect on cardiac biomarkers

the comparison of Effect of calcitriol and cholecalciferol on cardiac biomarkers in patients undergoing elective percutaneous coronary intervention, a randomized controlled study

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150518022306N3
Enrollment
180
Registered
2020-08-20
Start date
2020-07-22
Completion date
Unknown
Last updated
2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery disease. Atherosclerotic heart disease of native coronary artery

Interventions

Intervention 1: Intervention group: recieving 300000 internatinal unit cholecalciferol orally 12 hours before Percutaneous Coronary Intervention (Daana Pharma). Intervention 2: Intervention group: rec

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: All patients diagnosed with Coronary artery disease who hospitalized due to performing elective percutaneous Coronary Intervention (angioplasty with stent) Vitamin D level of less than 30 ng/mL

Exclusion criteria

Exclusion criteria: patients with myocardial infarction or history of coronary artery bypass graft in last 3 months patients with history of vitamin D supplementation in the last 1 month prior to hospitalization patients with history of unsuccessful PCI

Design outcomes

Primary

MeasureTime frame
Comparison any change in level of troponin-I. Timepoint: at baseline and 24 hours after Percutaneous Coronary Intervention. Method of measurement: serum level.;Comparison any change in level of High Sensitivity C-Reactive Protein (hsCRP). Timepoint: At baseline and 24 hours after Percutaneous Coronary Intervention. Method of measurement: serum level.;Comparison any change in level of Creatine kinase-MB. Timepoint: At baseline and 24 hours after Percutaneous Coronary Intervention. Method of measurement: serum level.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Laleh Mahmoudi

Shiraz University of Medical Sciences

Mahmoudi_l@sums.ac.ir+98 71 3242 4127

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026