Cognition disorder due to Electro Convalsive Therapy. Degenerative disease of nervous system, unspecified
Conditions
Interventions
Treatment - Drugs
Intervention 1: First group:A day before starting the study 4 mg of Galantamine every 12 hours prescript and 24 hour later achive to 8 mg every 12 hours.although a day befor starting the study 5 mg of
First group:A day before starting the study 4 mg of Galantamine every 12 hours prescript and 24 hour later achive to 8 mg every 12 hours.although a day befor starting the study 5 mg of Memantine every
Second group:A day before starting the study 4 mg of Galantamine every 12 hours prescript and 24 hour later achive to 8 mg every 12 hours.although a day befor starting the study 5 mg of Placebo every
Third group:A day before starting the study 5mg of Memantine every 12 hours prescript and 24 hour later achive to 10 mg every 12 hours.although a day befor starting the study 4 mg of Placebo every 12
Fourth group:A day before starting the study 4 mg of Placebo every 12 hours prescript and 24 hour later achive to 8 mg every 12 hours.although a day befor starting the study 5 mg of Placebo every 12 h
Sponsors
Ahvaz Jundishapur University of Medical Sciences
Ahvaz Jundishapur of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion critria: Aged between 60-18 years- the number of ECT sessions between 6 and 12- live in the city of Ahvaz. Exclusion criteria: alcohol and drug dependency orabuse during the 3 months prior to admission (except nicotine or caffeine)- diseases of the ducumented (kidney fixed Renal Failure)- epilepsy- Mental Retardation based on clinical assessment and evaluation by phicisian(resident)- delirium- dementia and cognitive disorders- pregnancy and breast feeding-use of memantine and galantamine than 3 months prior to admission- patients receiving thiazide diuretics- ducumented history and drug sensitivity effects with memantine and galantamine .
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Galantamine-Memantine-ECT numbers-MMSE Test score. Timepoint: One day before and one day after Electro Convalsive Therapy. Method of measurement: Questionary scors MMSE-Questionary Digit Span of Wechsler. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr.Heshmatolah Rahimi
Ahvaz Jundishapur of Medical Science
Outcome results
None listed