Post chemotherapy neutropenia in cancer patients. Agranulocytosis
Conditions
Interventions
Intervention 1: Group 1: will take subcutaneous/Iv injection of filgrastim 5 microgram/kg daily as well as Allium extract capsule twice daily containing equal to 1200 miligram allium powder. The cap
Treatment - Drugs
Placebo
Group 1: will take subcutaneous/Iv injection of filgrastim 5 microgram/kg daily as well as Allium extract capsule twice daily containing equal to 1200 miligram allium powder. The capsules will be c
Group 2 (control):50 patients are included in this group. They will be treated with filgrastim 5microgram/kg sc/IV injection daily the same as group1. However, instead of Allium capsule they will be g
Sponsors
Vice-chancellor of research of Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
4 Years to 18 Years
Inclusion criteria
Inclusion criteria: All children in the age range of 4-18 years who suffer from any kind of cancer and admitted post chemotherapy with febrile neutropenia are included. Those with known history of severe hypersensitivity reaction to the leek vegetable or other family members of garlic are excluded.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Absolute neutrophil count. Timepoint: daily. Method of measurement: CBC, diffrential. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hospital stay. Timepoint: at the time of discharge from hospital. Method of measurement: calculation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactmohammadreza bordbar
medical school
Outcome results
None listed