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Effect of aspirin for prevention of preeclampsia in women with abnormal ultrasonic findings in uterine artery

The effect of aspirin adminstration for prevention of preeclampsia in pregnant women with abnormal findings in uterine artery doppler sonography

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201505103025N5
Enrollment
100
Registered
2015-06-08
Start date
2014-09-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Preeclampsia. Condition 2: Preeclampsia. Gestational [pregnancy-induced] hypertension without significant proteinuria Gestational [pregnancy-induced] hypertension with significant proteinuria

Interventions

Intervention 1: Intervention Group: aspirine tablet 80 mili gram daily after 14-16 week of gestation until 37 week of pregnancy. Intervention 2: Control Group: placebo tablet daily after 14-16 week of
Prevention
Placebo
Intervention Group: aspirine tablet 80 mili gram daily after 14-16 week of gestation until 37 week of pregnancy
Control Group: placebo tablet daily after 14-16 week of gestation until 37 week of pregnancy

Sponsors

Vice-Chancellor for Research of Qazvin University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 42 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: pregnant women; singletone; gestational age 11-15 weeks; abnormal finding in uterine artery doppler sonography exclusion criteria: underlying medical condition; history of asthma; allergic to aspirin; termination of pregnancy before 20 weeks of pregnancy

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Preeclampsia. Timepoint: Measurement of Blood pressure every two weeks until 28 w then every week until termination of pregnancy. Method of measurement: Barometer, mmHg.

Secondary

MeasureTime frame
Intrauterine Growth Retardation. Timepoint: Every two weeks until 28 w then every week until termination of pregnancy. Method of measurement: Doppler Ultrasound If fetal growth retardation is suspected.;1 and 5 min apgar. Timepoint: 1 and 5 min after birth. Method of measurement: Standard apgar score.;Neonatal Weight. Timepoint: After Birth. Method of measurement: Digital Scale(gram).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarideh Movahed

Qazvin University of Medical Sciences

fmovahed@qums.ac.irdrmovahed@yahoo.com+98 28 3333 6001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026