Vasopressin effect in asystole rhythm patients

Effect of vasopressin and epinephrine in cardiac arrest outcomes in patients with asystole rhythm

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015050922181N1

Enrollment

210

Registered

2015-06-30

Start date

2011-03-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac arrest. Cardiac arrest with successful resuscitation

Interventions

Intervention 1: Intervention group: Vasopressin 40 unit intravenous will be pushed in asystole group patients. If there is no response, epinephrine will be pushed every 5 minutes. Intervention 2: Con

Treatment - Drugs

Intervention group: Vasopressin 40 unit intravenous will be pushed in asystole group patients. If there is no response, epinephrine will be pushed every 5 minutes.

Control group: Epinephrine 1 mg intravenous will be pushed in asystole group patients. If there is no response, epinephrine will be pushed every 5 minutes.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with Asystole rhythm Exclusion criteria: Ventricular Fibrilation; Pulssless Ventricular Tachycardia; Pulseless Electrical Activity; no resuscitation; Pregnancy; Hemorrhagic shock; CPR after 20 minutes

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Return of Spontaneous Circulation. Timepoint: After cardiac rhythm change. Method of measurement: Carotid pulse check.;Heart rate per minute. Timepoint: After return of circulation. Method of measurement: Cardiac monitoring.;Patient survival time. Timepoint: First hour, First day, First month. Method of measurement: Patient survival (having respiration and cardiac rhythm).;Total patient survival time. Timepoint: After return of circulation. Method of measurement: Minute.	—

Measure

Time frame

Return of Spontaneous Circulation. Timepoint: After cardiac rhythm change. Method of measurement: Carotid pulse check.;Heart rate per minute. Timepoint: After return of circulation. Method of measurement: Cardiac monitoring.;Patient survival time. Timepoint: First hour, First day, First month. Method of measurement: Patient survival (having respiration and cardiac rhythm).;Total patient survival time. Timepoint: After return of circulation. Method of measurement: Minute.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdi Torabi

Kerman University Medical Sciences

mtorabi1390@yahoo.com+98 34133151912

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026