Tissue adhesives for surgical wound closures

A clinical trial to compare suture vs. cyanoacrylate tissue glue for wound closure in mandibular third molars surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015050722139N1

Enrollment

Registered

2015-06-10

Start date

2014-09-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Impacted teeth. embedded and impacted teeth with abnormal position of such teeth or adjacent teeth

Interventions

Intervention 1: using tissue adhesive 2 ethyl- cyanoacrylate( EPIGLU, Meyer-Haake Co. Germany) for wound closure in intervention group. adhesive was used according to package insert. Intervention 2: i

Treatment - Surgery

using tissue adhesive 2 ethyl- cyanoacrylate( EPIGLU, Meyer-Haake Co. Germany) for wound closure in intervention group. adhesive was used according to package insert.

in group control suture was used for wound closure.Non absorbable Suture Silk 0/3 was used for wound closure.simple interrupted suture technique used to close wounds. (supasil-3\0 usp- non-absorbabl

Eligibility

Sex/Gender

All

Age

19 Years to 25 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: -After taking panoramic radiography patients with impacted 3rd molar with mesioangular or vertical impaction, vertical class c pell & gregory and anterior posterior class 2 pell & gregory impaction were selected. -Patients must be younger than 25 years old -No systemic disease,no wound healing disruptive disease,no diabetes, no bleeding disorders -No history of anticoagulant medicines, no use of immunosuppressant drugs. -No history of smoking and drinking -No decays on 2nd molar

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: 1,2,3,5,7 days after surgery. Method of measurement: with pain visual analog scale questionnaire.;Bleeding. Timepoint: 1,2,3 days after surgery. Method of measurement: with bleeding questionnaire.;Wound healing. Timepoint: first and second weeks after surgery. Method of measurement: oral and maxillofacial surgeon's view.	—

Secondary

Measure	Time frame
Patient comfort. Timepoint: first week after surgery. Method of measurement: according to patients' reports.;Sensitivity of soft tissue. Timepoint: first and second weeks after surgery. Method of measurement: evaluated by oral and maxillofacial surgeon.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBenika Abbasi

Jondishapur university of medical science

Abbasi.b@ajums.ac.ir+98 935 918 0832

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026