Maternal hypotension. Maternal hypotension syndrome
Conditions
Interventions
Intervention 1: Bolus injection of 5 mg ephedrine if hypotension is more than 20% from baseline and If necessary, repeat dose, 5 mg. Intervention 2: Bolus injection of 10 mg ephedrine if hypotension
Treatment - Drugs
Bolus injection of 5 mg ephedrine if hypotension is more than 20% from baseline and If necessary, repeat dose, 5 mg
Bolus injection of 10 mg ephedrine if hypotension is more than 20% from baseline and If necessary, repeat dose,10 mg
Bolus injection of 50µg phenylephrine if hypotension is more than 20% from baseline and If necessary, repeat dose, 50µg
Bolus injection of 100 µg phenylephrine if hypotension is more than 20% from baseline and If necessary, repeat dose, 100 µg
Sponsors
Vice Chancellor Of Research Zahedan University Of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 35 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria:Pregnant women 2o-35 years old ;Elective cesarean;ASA1; Singleton pregnancy;36 to 40 weeks gestational age;Weighing 45 to 90 kg;145 to 180 cm height;Informed consent for inclusion Exclusion criteria beginning: History of Primary hypertension (Bp=140/90);cardio-cerebrovascular diseases; Diabetic mellitus;Sensitivity to anesthetics;Pregnancy complications such as gestational hypertension;Placental abnormalities;Umbilical cord abnormalities;High-risk pregnancies(Multiple pregnancy?Intrauterine growth retardation);Spinal anesthesia ban(Prevention of spinal anesthesia?Coagulation disorder?Infection of spinal anesthesia area);Lack of consent to participate in the study Exclusion criteria during the study:Unpredictable events during surgery such as abnormal hemorrhage under surgery; unsuccessful spinal anesthesia;high spinal Anesthesia (at level above T4); more than 75min surgery duration
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure. Timepoint: After spinal anesthesia,75 minutes (every 3 minutes for the first 15-minute period and every 10 minutes for the following 60-minute period. Method of measurement: mmHg by SIEMENS SC 7000 monitoring system.;Heart rate. Timepoint: After spinal anesthesia, were checked for 75 minutes (every 3 minutes for the first 15-minute period and every 10 minutes for the following 60-minute period. Method of measurement: Number by SIEMENS SC 7000 Monitoring system. | — |
Secondary
| Measure | Time frame |
|---|---|
| Base Exess. Timepoint: After the extraction of fetus and umbilical cord clamp. Method of measurement: Number -Based on the arterial umbilical cord Base Exess,that was measured by blood gas analyzer ,GASTAT-603ie.;Nausea. Timepoint: During Surgery. Method of measurement: Has/has not,Patient-reported.;Vomiting. Timepoint: During Surgery. Method of measurement: Has/has not,Observer-reported.;Umbilical cord Ph. Timepoint: After the extraction of fetus and umbilical cord clamp. Method of measurement: Number -Based on the arterial umbilical cord PH,that was measured by blood gas analyzer ,GASTAT-603ie.;Neonatal Apgar. Timepoint: At 1 and 5 minutes after birth. Method of measurement: Based on clinical examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHedayatollah Vakili
Zahedan University of Medical Sciences
Outcome results
None listed