Effectiveness of splinting and local steroid injection in severe carpal tunnel syndrome

Comparative assessment of splinting and splinting plus local steroid injection outcomes in severe carpal tunnel syndrome

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015050622130N1

Enrollment

Registered

2015-07-19

Start date

2013-06-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

carpal tunnel syndrome. Carpal tunnel syndrome

Interventions

Intervention 1: One group (group A) is prescribed to use full time neutral wrist splint for 12 weeks. Intervention 2: In group B using sterilized method and a 25G needle, 40mg methylprednisolone aceta

Treatment - Other

Treatment - Drugs

One group (group A) is prescribed to use full time neutral wrist splint for 12 weeks.

In group B using sterilized method and a 25G needle, 40mg methylprednisolone acetate (Depomedrol) is injected to the wrist-flexon crease just ulnar to the palmaris longus tendon. The needle is introdu

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients with signs and symptoms of CTS aged =18 years?electrodiagnostic evidences of moderate to severe CTS. Exclusion criteria: Patients with secondary causes of CTS (diabetes mellitus? thyroid dysfunction? malignancy? distal radius fracture? pregnancy)? conditions affecting treatment outcomes (cervical disc herniation? fibromyalgia? coexisting neuropathy? previous steroid injection into the affected wrist)? patients with thenar muscles atrophy due to advanced CTS.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Clinical and functional status. Timepoint: baseline, 4 weeks and 12 weeks later. Method of measurement: Boston Questionnaire.;Electrodiagnostic findings. Timepoint: baseline and 12 weeks later. Method of measurement: electromyography instrument.;Patients satisfaction. Timepoint: baseline, 4 weeks and 12 weeks later. Method of measurement: Likert scale.	—

Secondary

Measure	Time frame
Local steroid injection complications. Timepoint: after injection,4 weeks and 12 weeks later. Method of measurement: patients complaints and physical examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Sayed Amir Ebrahim Mahmoodian

Isfahan University of Medical Sciences, Medical faculty

Dean@med.mui.ac.ir+98 31 3668 8466

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026