Condition 1: head Injuries. Condition 2: head Injuries. Intracranial injury, unspecified Unspecified injury of head
Conditions
Interventions
Intervention 1: Intervention group treat with ondansetron (4mg/2ml, slow injection). 20 minutes post drug administration, nausea level will measure again. If the severity of nausea not decrease at lea
Treatment - Drugs
Intervention group treat with ondansetron (4mg/2ml, slow injection). 20 minutes post drug administration, nausea level will measure again. If the severity of nausea not decrease at least by 20 mm comp
Cotrol group treat with metoclopramide (10mg/2ml, slow injection) and treatment with ondansetron (4mg/2ml, slow injection). 20 minutes post drug administration, nausea level will measure again.
Sponsors
Isfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 139 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria : minor head trauma; nausea and vomiting; and a triage level of 3 or higher based on emergency severity score; exclusion criteria : hemodynamic instability; pregnancy/lactation; any neurologic deficit; restlessleg syndrome; alcohol usage; consumption of any antiemetic drugs during the 8 hours prior to admission; chemotherapy or radiotherapy; inability to complete and understand study explanations or outcome measures; allergy or previous adverse reactions to metoclopramide or ondansetron;
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nausea Severity. Timepoint: before drug injection and 20 minutes after drug injection. Method of measurement: Visual Analogue Scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Dystonia. Timepoint: before drug injection and 20 minutes after drug injection. Method of measurement: Physical Examination.;Fatigue. Timepoint: before drug injection and 20 minutes after drug injection. Method of measurement: Physical Examination.;Headache. Timepoint: before drug injection and 20 minutes after drug injection. Method of measurement: Visual AnalogueScale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMehrdad Esmailian
Isfahan University of Medical Sciences
Outcome results
None listed