Bacterial sepsis of newborn. Bacterial sepsis of newborn
Conditions
Interventions
Antibiotic therapy with ampicilin+amikacin or rarely vancomycin+meropenem.
Treatment - Drugs
Antibiotic therapy with ampicilin+amikacin or rarely vancomycin+meropenem
Sponsors
Shahed university
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
No minimum to 28 Days
Inclusion criteria
Inclusion criteria: Inclusion criteria: All healthy full-term babies, having healthy mothers and normal Apgar scores, suspected of sepsis and candidates for antibiotic treatment in the NICU of Vali-e Asr Hospital. Exclusion criteria: Infants with positive blood cultures, infants with positive cerebrospinal fluid culture, infants being treated with corticosteroids, infants whose mothers were treated with corticosteroids or magnesium sulphate at least one week prior to delivery, infants whose mothers received antibiotics prior to delivery, cord acidosis and birth asphyxia, infants that are intravenously fed, and infants of ill mothers.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IL-1ß. Timepoint: just before and 12 hrs after intervention. Method of measurement: ELISA,pg/ml.;IL-6. Timepoint: just before and 12 hrs after intervention. Method of measurement: ELISA,pg/ml.;IL-8. Timepoint: just before and 12 hrs after intervention. Method of measurement: ELISA,pg/ml.;TNF-a. Timepoint: just before and 12 hrs after intervention. Method of measurement: ELISA,pg/ml. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactGolnaz Rezaeizadeh
Maternal Fetal Neonatal Research Center,Tehran University of Medical Sciences
Outcome results
None listed