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Analgesic Effect of Morphine and Acetaminophen

Comparison of the Analgesic Effect of Intravenous Acetaminophen and Morphine Sulfate in Rib Fracture

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015042812072N2
Enrollment
54
Registered
2015-05-24
Start date
2013-03-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rib fracture. Fracture of rib

Interventions

Intervention 1: Intervention group treat with IV acetaminophen (1gram per kilogram of body weight, single-dose, and infused in 100 cc normal saline). If the pain will not relieved after the first 30 m
Treatment - Drugs
Intervention group treat with IV acetaminophen (1gram per kilogram of body weight, single-dose, and infused in 100 cc normal saline). If the pain will not relieved after the first 30 minutes, a rescue
Control group treat with morphine sulfate (0.1 milligram per kilogram of body weight, single-dose, and infuse in 100 cc normal saline). If the pain will not relieved after the first 30 minutes, a res

Sponsors

Isfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria : one or two rib fractures confirmed by chest radiography; normal level of con-sciousness (Glasgow Coma scale of 15); weight range be-tween 60-100 kilogram; pain score>4 centimeters based on Numeric Rating Scale; Exclusion criteria : background pulmonary problems; history of taking analgesic or opioid drugs; addiction; history of liver or kidney diseases; head trauma; pregnancy; respiratory arrest on arriva;l repeated vomiting and nausea

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain accuity. Timepoint: at start and 30 minute after intervention. Method of measurement: Numeric Rating Scale.

Secondary

MeasureTime frame
Vital signs. Timepoint: at start and 30 minute after intervention. Method of measurement: manomter and pulse checking.;O2 saturation. Timepoint: at start and 30 minute after intervention. Method of measurement: PulseOxymtery.;Drug Complications. Timepoint: at start and 30 minute after intervention. Method of measurement: History and physical examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehrdad Esmailian

Isfahan University of Medical Sciences

m_esmailian@med.mui.ac.ir+98 31 3629 3482

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026