Ultrasonographic ?Evaluation of lung Recruitability in Acute Respiratory Distress Syndrome

Evaluation of Ultrasonographic lung Recruitibility with Two Types of Positive End Expiratory Pressure Selection in Moderate to Severe Acute Respiratory Distress Syndrome

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20150427021981N1

Enrollment

Registered

2018-04-04

Start date

2018-01-21

Completion date

Unknown

Last updated

2018-04-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Respiratory Distress Syndrome. Acute respiratory distress syndrome

Interventions

Intervention and control group: Use of positive end expiratory pressure according to"low PEEP table" in ARDS net protocol during mechanical ventilation (control group) and then (after 30 minutes), Use

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with Moderate to Severe Acute Respiratory Distress Syndrome and under invasive mechanical ventilation

Exclusion criteria

Exclusion criteria: Younger than 18 year Less than 24 h or more than 96 h after the onset of the disease. Unstable hemodynamic Contraindication for using of high PEEP Known heart failure Acute ischemic heart disease or uncontrolled arrythmia Chronic lung disease BMI>40

Design outcomes

Primary

Measure	Time frame
Lung recruitability (Reaeration) with two type of positive end expiratory pressure selection. Timepoint: Initial measurement of lung recruitment (Reaeration) with a low level of positive end expiratory pressure (low PEEP table) and after 30 minutes with a high positive end expiratory pressure level (Express trial). Method of measurement: By lung ultrasonography with 2.5 to 5 megahertz curve probe.	—

Measure

Time frame

Lung recruitability (Reaeration) with two type of positive end expiratory pressure selection. Timepoint: Initial measurement of lung recruitment (Reaeration) with a low level of positive end expiratory pressure (low PEEP table) and after 30 minutes with a high positive end expiratory pressure level (Express trial). Method of measurement: By lung ultrasonography with 2.5 to 5 megahertz curve probe.

—

Secondary

Measure	Time frame
Oxygenation state. Timepoint: Five minutes after positive end expiratory pressure (PEEP) change. Method of measurement: Dividing the arterial oxygen pressure to the fraction of inspired oxygen (Po2/Fio2 ratio).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAhmad bagheri moghaddam

Mashhad University of Medical Sciences

bagheriA@mums.ac.ir+98 51 3760 6328

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026