The effect of Liothyronine in patients with mood disorder undergoing electroconvulsive therapy

Clinical trial the effect of the cognitive protective effect of Liothyronine Cognitive Protective Effect in Patients with Mood Disorder treated with Electroconvulsive therapy

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20150427021965N11

Enrollment

Registered

2019-08-09

Start date

2019-08-06

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Mood disorder (Manic episode). Condition 2: Mood disorder (Bipolar disorder). Condition 3: Mood disorder (depression). Manic episode Bipolar disorder Major depressive disorder, single episode

Interventions

Intervention 1: Intervention group: Individuals in intervention group will receive for 6 sessions a Electroconvulsive therapy (ECT) and for 6 weeks two Liothyronine tables(25mcg, daily). Interventio

Eligibility

Sex/Gender

All

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Diagnosis of mood disorder according to DSM 5 criteria Not being pregnant Age 18 to 45 years

Exclusion criteria

Exclusion criteria: Increases ECT more than 6 sessions ECT-induced delirium The patient's unwillingness to cooperate

Design outcomes

Primary

Measure	Time frame
Cognitive status. Timepoint: Patients were evaluated at baseline, at the end of the intervention and 6 weeks later. Method of measurement: Patients are evaluated using Wechsler Memory Scale and Mini-mental state examination (MMSE).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKiomars Najafi

Rasht University of Medical Sciences

kkiomars@yahoo.com+98 13 3366 6268

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026