Preterm Labor. Preterm spontaneous labour with preterm delivery
Conditions
Interventions
Intervention 1: Intervention group: initial dose 4 g of magnesium sulfate intravenously and then continuation of magnesium sulfate administration at a dose of 2g per hour for 24 hours with a 100 mg c
Prevention
Placebo
Intervention group: initial dose 4 g of magnesium sulfate intravenously and then continuation of magnesium sulfate administration at a dose of 2g per hour for 24 hours with a 100 mg celecxib capsule
Control group: initial dose 4g of magnesium sulfate intravenously and then continuation of magnesium sulfate administration at a dose of 2g per hour for 24 hours with a placebo capsule and if needed
Sponsors
Vice-Chancellor for Research of Qazvin University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 46 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Singleton pregnancy; Intact amniotic membrane; Gestational age between 24-34 weeks; Positive tocometry. Exclusion criteria: PROM; Vaginal bleeding; Chorioamnionitis; Dilatation more than 2 cm and cervical effacement exceeding 80%; Polyhydramnios; Oligohydramnios; Intrauterine Fetal Demise; Intrauterine Growth Restriction; Fetal distress; Smoking and alcohol abuse; systemic disease; Congenital anomalies; uterine anomalies; Celecxib intolerance.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Preterm Labor. Timepoint: One hour after the onset of drug use until 24 hours. Method of measurement: Tocometer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarideh Movahed
Qazvin University of Medical Sciences
Outcome results
None listed