Allergic rhinitis. Vasomotor and allergic rhinitis
Conditions
Interventions
Intervention 1: Intervention group: Participants in this group receive one daily capsule of the probiotic supplement ProKid for four weeks. The supplement contains Lactobacillus acidophilus, Lactobaci
Sponsors
Oroumia University of Medical Sciences
Eligibility
Sex/Gender
All
Age
5 Years to 18 Years
Inclusion criteria
Inclusion criteria: Children aged 5 to 18 years with allergic rhinitis Presence of clinical symptoms of allergic rhinitis including sneezing, nasal itching, rhinorrhea, or nasal congestion Diagnosis of allergic rhinitis confirmed by an Allergy and Immunology specialist No use of probiotic supplements within 4 weeks prior to study enrollment No use of antibiotics within 4 weeks prior to study enrollment No history of chronic gastrointestinal diseases No history of autoimmune diseases No history of immunodeficiency disorders
Exclusion criteria
Exclusion criteria: Non-compliance with regular consumption of probiotic supplements or placebo Occurrence of severe adverse effects related to probiotic supplementation Modification of the primary allergic rhinitis treatment by the treating physician during the study period
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of allergic rhinitis clinical symptoms including sneezing, rhinorrhea, nasal itching, and nasal congestion. Timepoint: Measurement at baseline before the intervention and at the end of the fourth week after the intervention. Method of measurement: Total Nasal Symptom Score questionnaire.;Allergy related quality of life in children with allergic rhinitis. Timepoint: Measurement at baseline before the intervention and at the end of the fourth week after the intervention. Method of measurement: Mini Rhinoconjunctivitis Quality of Life Questionnaire.;Total serum Immunoglobulin E level. Timepoint: Measurement before the intervention and at the end of the fourth week after the intervention. Method of measurement: Serum laboratory assay for measurement of total Immunoglobulin E. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contact??Dr. Hamid Reza Houshmand
Oroumia University of Medical Sciences
Outcome results
None listed