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Comparing the efficacy of a combination of Mometasone and Olopatadine sprays versus Mometasone spray in children with allergic rhinitis

Comparing the efficacy of a combination of Mometasone and Olopatadine sprays versus Mometasone spray in children with allergic rhinitis

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150426021944N5
Enrollment
80
Registered
2024-05-31
Start date
2024-06-19
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergic rhinitis. Vasomotor and allergic rhinitis

Interventions

Intervention 1: Intervention group: Patients receiving two sprays of mometasone and allanthin with doses of 25 micrograms and 665 micrograms twice a day (every 12 hours). Intervention 2: Control group

Sponsors

Oroumia University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 12 Years

Inclusion criteria

Inclusion criteria: Allergic rhinitis diagnosis by a clinical allergist collaborating in the project (based on the presence of clinical symptoms such as sneezing, nasal congestion, nasal secretions, and nasal itching or based on a positive prick test or a positive IgE specific to allergens) Age 6-12 years old Obtaining written informed consent from parents

Exclusion criteria

Exclusion criteria: Known history of nasal polyps, other clinically significant respiratory system abnormalities Structural abnormalities of the nose Septum deviation Chronic, acute, or significant sinusitis or post-nasal drip (PND) Drug-induced rhinitis; active pulmonary disorder or infection (e.g., bronchitis, pneumonia, or influenza) Upper respiratory tract or sinus infection within the past 14 days Other important clinical abnormalities of the respiratory system

Design outcomes

Primary

MeasureTime frame
Quality of life. Timepoint: Days 7, 1 and 14 after intervention. Method of measurement: Pediatric Rhino Conjunctivitis Quality of Life Questionaire( PRQLQ).

Secondary

MeasureTime frame
TNSS questionnaire. Timepoint: Days 7, 1 and 14 after the intervention. Method of measurement: TNSS questionnaire(Total Nasal Symptom Score: TNSS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamidreza Hoshmand

Oroumia University of Medical Sciences

motahari-h-urm@umsu.ac.ir+98 44 3223 7080

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026