Intraventricular hemorrahge. Intracranial (nontraumatic) haemorrhage of fetus and newborn, unspecified
Conditions
Interventions
Intervention 1: In Intervention group we prescribed 10 unit of Vit E ( equall to 1 cc) orally via orogastric tube once in day for 3 days. Intervention 2: In control group we prescribed 1 cc of disti
Prevention
Placebo
In Intervention group we prescribed 10 unit of Vit E ( equall to 1 cc) orally via orogastric tube once in day for 3 days
In control group we prescribed 1 cc of distilled water orally via orogastric tube once in day for 3 days
Sponsors
Vice Chancellor for research of Isfahan University of Medical Sciense
Eligibility
Sex/Gender
All
Age
No minimum to 1 Months
Inclusion criteria
Inclusion criteria: Inclusion criteria: preterm infants with gestational age less than 30weeks; lack of congenital malformations or CNS disease at birth; the infant's mother take one course of steroid prior to delivery; absent of maternal chorioamnionitis; lack of use of mechanical ventilation; oxygen saturation greater than 90%; normal blood pressure; APGAR score greater than 7 at 5 minute; lack or sepsis; lack of IVH at the beginning of study; lack of abdominal distention at the beginning of study. Exclusion criteria: need for administration of sodium bicarbonate during first 3 days of birth; need of resuscitation during first 3 days of birth; abdominal distention during vit E administration; need for mechanical ventilation.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intra Ventricular Hemorrahge. Timepoint: 4th and 7th days. Method of measurement: Brain Sonography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Sepsis. Timepoint: During Study. Method of measurement: Clinical Sign and Blood Culture.;Necrotizing Enterocolitis. Timepoint: During Study. Method of measurement: Clinical Sign and Abdominal Graphy.;Death. Timepoint: During Study. Method of measurement: Observation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSamira Saraeian
Isfahan University of Medical Sciences
Outcome results
None listed