Skip to content

Impact of intrauterine injection of G-csf on implantation and clinical pregnancy rate in repeated implantation failure

Impact of intrauterine injection of G-csf on implantation and clinical pregnancy rate in repeated implantation failure

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015042312146N6
Enrollment
68
Registered
2015-04-28
Start date
2015-05-05
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female Infertility.

Interventions

Intervention 1: In the control group: Endometrial preparation starts with the Estradiol valerate 4 mg tablet once a day and after three days to 6 mg per day increases. Endometrial thickness is determi
Treatment - Drugs
In the control group: Endometrial preparation starts with the Estradiol valerate 4 mg tablet once a day and after three days to 6 mg per day increases. Endometrial thickness is determined by ultrasoun
In the case group: Before progesterone injection in study group 100 micrograms G-CSF with IUI catheter as infusion intrauterine. Three days after the injection of progesterone transferred embryo

Sponsors

Vice chancellor for Research,Tabriz University Of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age 45-18 , and personal satisfaction; Had two or more failures of implantation Exclusion criteria: patients with a history of uterine surgery; hydrosalpinges; endometriosis; Endometrial polyps; Submucosal myoma; Contraindications G-CSF as:Kidney failure; Chronic Neutropenia;anemia; Cancer; Pneumonia.

Exclusion criteria

Exclusion criteria:

Design outcomes

Secondary

MeasureTime frame
Clinical pregnancy. Timepoint: Two weeks after positive BHCG. Method of measurement: Vaginal ultrasound.

Primary

MeasureTime frame
Implantation rates. Timepoint: Two weeks after embryo transfer. Method of measurement: Ultrasound.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Farzadi Laaya

Tabriz University Of Medical Sciences

farzadl@yahoo.com; lahroudin@gmail.com+98 41 3556 9543

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026