Cutaneous leishmaniasis. Cutaneous leishmaniasis
Conditions
Interventions
Intervention 1: Nano Liposome Amphotricin B. Intervention 2: Treatment with topical nano liposomal form of Amphotericin B twice a day for 28 days.
Treatment - Drugs
Nano Liposome Amphotricin B
Treatment with topical nano liposomal form of Amphotericin B twice a day for 28 days
Sponsors
MoH, EMRO/WHO
Eligibility
Sex/Gender
All
Age
12 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Inclusion criteria: Male or female aged between 12 to 60 years. Parasitologically proven CL due to L. tropica. In general good health based on history and physical examination. Number of lesion at most 5. Lesion size less than 3 cm. Signed informed consent voluntarily and knowingly**. ** Guardian’s signature for volunteer less than 18 years old. Exclusion criteria: Pregnancy lactating women Use of other types of treatment for CL. Involvement in any other drug or vaccine trial during the study period. Known heart, kidney, liver diseases based on history and physical exam.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete cure. Timepoint: at week 4, 8, and days 90 and 180. Method of measurement: measurement of lesion status. | — |
Secondary
| Measure | Time frame |
|---|---|
| Lesion(s) partial cure. Timepoint: at week 4, 8 and days 90 and 180. Method of measurement: measurement of lesion size. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Mohammad Hossein Ghoorchi
Mashhad University of Medical Sciences
Outcome results
None listed