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The effect of Q10 on breast cancer treatment

Effect Of Coenzyme Q10 Supplementation On Serum LevelsOf Interleukin 6, 8, Vascular Endothelial Growth Factor And Quality Of Life In Breast Cancer Women Undergoing Tamoxifen Therapy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015042021874N1
Enrollment
60
Registered
2015-10-08
Start date
2015-10-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer. Malignant neoplasm of breast

Interventions

Intervention 1: Intervention group of patients: 100 mg Q10 daily for 2 months. Intervention 2: Intervention group of non patients: 100 mg Q10 daily for 2 months. Intervention 3: Control group of pati
Treatment - Drugs
Intervention group of patients: 100 mg Q10 daily for 2 months
Intervention group of non patients: 100 mg Q10 daily for 2 months
Control group of patients: placebo for 2 months
Control group of non patients: placebo for 2 months

Sponsors

Vice Chancellor for research of Ahvaz University of Medical Sciences
Lead Sponsor
Nutrition and Metabolic Disorders Research Center
Collaborator

Eligibility

Sex/Gender
Female
Age
19 Years to 49 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria : diagnosed with positive estrogen receptor breast cancer by a physician; chemotherapy and radiation therapy, and a history of taking tamoxifen for at least a year; Not taking Q10 supplement and other antioxidants such as vitamin E; Willingness to comply with all interventions and follow-up procedures; Non-pregnant and non-lactating; Having no uncontrolled diseases such as diabetes and thyroid; Not taking non-prescription drugs, corticosteroids, statins Exclusion criteria : metastasis; partial or total mastectomy and not having any of the above entry criteria

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Quten serum levels. Timepoint: Before intervention. Method of measurement: Pg/ml using biochemical kits.;Interluekin 6 serum levels. Timepoint: Before and after intervention. Method of measurement: Pg/ml using biochemical kits.;Interluekin 8 serum levels. Timepoint: Before and after intervention. Method of measurement: Pg/ml using biochemical kits.;VEGF serum levels. Timepoint: Before and after intervention. Method of measurement: Pg/ml using biochemical kits.;Quality of life. Timepoint: Before and after intervention. Method of measurement: Breast cancer Quality of Life Questionnaire.

Secondary

MeasureTime frame
Weight. Timepoint: Before and after intervention. Method of measurement: Scale.;Dietary intake. Timepoint: Before and after intervention. Method of measurement: Three-day record.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNazanin Zahrooni

Paramedical Faculty

Zahrooni.n@ajums.ac.ir; Naziincredible@rocketmail.com+98 916 802 8250

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 20, 2026