Refractory Epilepsy. Episodic and paroxysmal disorders
Conditions
Interventions
Treatment - Other
In this study, patients suffering from refractory seizure are treated with classic KD. This type of treatment is continued according to the required response and tolerance .In Ketogenic Diet, 80 perce
Sponsors
Vice Chancellor for research of Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
2 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria:refractory epilepsy ; don't have contraindicated ; Above 2 years old. Exclusion criteria: inability to continue the ketogenic diet for 6 months.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma lipid profil. Timepoint: Before treatment and at three and six month after treatment. Method of measurement: TG; Total Chol; HDL; LDL by mg/dl. | — |
Secondary
| Measure | Time frame |
|---|---|
| Effect of KD on seizure control; urin random Ca; Cr; oxalate; uric acid; BLOOD ca; vitD; thyroid function tests; liver function tests; heart failure. Timepoint: Before treatment; 3 mounths; 6 months after treatment. Method of measurement: Seizure control by reduction in numbers of paroxysms; urine random Ca; urine random uric acid urinerandom oxalate; liver function tests; thyroid function tests; serum Ca and vit D by mg/dl; cardiovascular by ejection fraction that measured by litre per min. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr.Gholamreza Zamani
Chidren's Medical Centr Hospital
Outcome results
None listed