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the effect of synbiotic on seminal fluid

Efficacy of Synbiotic (FamiLact) as an Adjuvant Therapy in Improvement of Semen Parameters of Patients Undergoing Varicocelectomy: A Randomized Double-Blinded Controlled Trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150420021869N4
Enrollment
84
Registered
2021-08-06
Start date
2021-08-23
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility. Male infertility

Interventions

Intervention 1: Intervention group: In this group, patients receive one Familact capsule containing 500 mg of synbiotics made by Zist takhmir Pharmaceutical Company for 6 months. Intervention 2: Contr

Sponsors

Bagheiat-allah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Men with infertility who are candidates for unilateral varicocelectomy

Exclusion criteria

Exclusion criteria: Cryptorchidism Epididymitis and orchitis urogenital trauma prostatitis testicular torsion history of inguinal or genital surgery history of hormone therapy endocrinopathy history or current use of cytotoxic drugs, anti epileptic agent and androgens recent history of sexual transmitted disease

Design outcomes

Primary

MeasureTime frame
Seminal fluid volume. Timepoint: before varicocelectomy and 3 months after surgery. Method of measurement: seminal analysis.;Sperm count. Timepoint: before varicocelectomy and 3 month after varicocelectomy. Method of measurement: seminal analysis.;Sperm concentration. Timepoint: before varicocelectomy and 3 month after varicocelectomy. Method of measurement: seminal analysis.;Progressive sperm motility. Timepoint: before varicocelectomy and 3 month after varicocelectomy. Method of measurement: seminal analysis.;Sperm with normal morphology. Timepoint: before varicocelectomy and 3 month after varicocelectomy. Method of measurement: seminal analysis.;Fertility. Timepoint: 6month after varicocelectomy. Method of measurement: pregnancy.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarshad Gholipour

Esfahan University of Medical Sciences

gholipour@med.mui.ac.ir+98 31 3668 0048

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026