Male infertility. Male infertility
Conditions
Interventions
Intervention group: all patients are treated with 500 mg of Eskanbil extract in the form of oral capsule for three months..
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: Men aged 20 to 45 years Idiopathic infertility Sperm count less than 16 million per milliliter Total motility less than 42% or progressive motility less than 30% Normal sperm morphology less than 4%
Exclusion criteria
Exclusion criteria: Pyospermia History of testicular surgery History of chemotherapy or radiotherapy Cigarette smoking History or current use of medications affecting spermatogenesis, such as tamoxifen, hCG, cytotoxic drugs (e.g., immunosuppressants, anticonvulsants, androgens) History of sexually transmitted infections (STIs) History of epididymo-orchitis History of testicular trauma History of prostatitis Lack of willingness to participate in the study Chromosomal abnormalities History of testicular torsion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Semen volume. Timepoint: At baseline and 3 months after the intervention. Method of measurement: Semen analysis.;Sperm DNA fragmentation index. Timepoint: At baseline and 3 months after the intervention. Method of measurement: Tunnel test.;Sperm concentration. Timepoint: At baseline and 3 months after the intervention. Method of measurement: Semen analysis.;Sperm motility. Timepoint: At baseline and 3 months after the intervention. Method of measurement: Semen analysis.;Sperm morphology. Timepoint: At baseline and 3 months after the intervention. Method of measurement: Semen analysis. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarshad Gholipour
Esfahan University of Medical Sciences
Outcome results
None listed