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Effect of meloxicam on orthodontic pain

Comparison of the effects of preemptive acetaminophen, ibuprofen, and meloxicam on pain after separator placement: a randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015041821828N1
Enrollment
321
Registered
2015-06-05
Start date
2015-02-11
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post separator placement pain. acute pain

Interventions

Intervention 1: ibuprofen 400 mg orally one hour before separator placement. Intervention 2: acetaminophen 650 mg orally one hour before separator placement. Intervention 3: meloxicam 7.5 mg orally o
Treatment - Drugs
ibuprofen 400 mg orally one hour before separator placement
acetaminophen 650 mg orally one hour before separator placement
meloxicam 7.5 mg orally one hour before separator placement

Sponsors

Shiraz University of MedicalSscience
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to No maximum

Inclusion criteria

Inclusion criteria: inclusion criteria: not currently using antibiotics; analgesics, anti – inflammatory, anti-coagulative, diuretics, oral anti diabetics, lithium, cyclosporine and methotrexate; no need for antibiotic prophylaxis; no chronic systemic disease or clotting disorders; not reporting contraindication for NSAIDs; not pregnant or nursing exclusion criteria: use any analgesic during the study time

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Post separator pain. Timepoint: immediately, 2 hour, 6 hour, 24 hour and 48 hour after separator placement. Method of measurement: visual analogue scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNeda Babanouri

Shiraz University of Medical Science

stud 3961854483@sums.ac.ir+98 713230541019

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Mar 4, 2026