Effects of Ketorolac, Metoclopramide, Lidocaine on Reducing Pain During Propofol IV Injection

Comparison of the Effects of Ketorolac, Metoclopramide, Lidocaine on Reducing Pain During Propofol IV Injection in general anesthesia induction

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20150417021806N5

Enrollment

120

Registered

2020-08-30

Start date

2019-12-22

Completion date

Unknown

Last updated

2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain During Propofol IV Injection in general anesthesia induction. Acute pain, not elsewhere classified

Interventions

Intervention 1: Control group: After injection of 2 cc water, 30 milligram Propofol is injected at the rate of 0.5cc per second. Intervention 2: Intervention group 1: After injection of 40 milligram

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: patient 18-50 year old who candidate for elective surgery with ASA1 and ASA2

Exclusion criteria

Exclusion criteria: sedative , analgesic or narcotic agents consumption within 24 hours before surgery analgesic or narcotic drugs or alcohol abuse contraindications of lidocain, metochlopramide, ketorolac or other NSAIDs contraindications of propofol including alleric reaction to foods such as egg or soy bean chronic pain disorders neurologic or psychiatric disorders pregnancy unable to communicate verbally

Design outcomes

Primary

Measure	Time frame
Pain During Propofol IV Injection. Timepoint: Immediately after Propofol injection, before complete anesthesia, the severity of pain on injection is recorded. Method of measurement: Verbal Rating Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAbolfazl Abdollahpoor

Semnan University of Medical Sciences

abolfazlabdollahpoor@semums.ac.ir0098 23 31420

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026