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Comparison of venous acetaminophen and ketorolac on hemodynamics and respiration.

Comparison of intravenous acetaminophen and ketorolac effects on the airway response and investigates the hemodynamic fluctuation during extubation in patient undergoing elective surgery.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150417021806N4
Enrollment
80
Registered
2018-03-12
Start date
2018-04-04
Completion date
Unknown
Last updated
2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory complications. Intraoperative and postprocedural complications and disorders of respiratory system, not elsewhere classified

Interventions

Intervention 1: Intervention group 1, ketorolac is injected intravenously about half an hour before the end of surgery, at a dose of 0.5 mg/kg maximum, 30 mg per 15 seconds. Intervention 2: Interventi

Sponsors

Semnan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patient undergoing elective surgery Age between 20-60 year Patient satisfaction Insensitivity to acetaminophen and ketorolac

Exclusion criteria

Exclusion criteria: History of asthma Allergic to aspirin, acetaminophen and ketorolac History of kidney and liver disorders, History of ulcer and gastrointestinal bleeding, Coagulation disorders Pregnant and lactating women The need for another drug for anesthetic maintenance History of hypertension History of brain hemorrhage History of chronic cough difficult Intubation

Design outcomes

Primary

MeasureTime frame
Heart rate. Timepoint: Before injecting drug intervention, Before Injecting the Rivers and 5 minutes after extubation. Method of measurement: Count the patient's pulse rate in minutes.;Blood pressure. Timepoint: Before injecting drug intervention, Before Injecting the Rivers and 5 minutes after extubation. Method of measurement: Cuff pressure monitoring device.;Oxygen saturation. Timepoint: Before injecting drug intervention, Before Injecting the Rivers and 5 minutes after extubation. Method of measurement: Oximetry pulse.;Cough. Timepoint: Before injecting drug intervention, Before Injecting the Rivers and 5 minutes after extubation. Method of measurement: Minggo's 5-point scale.

Countries

Iran (Islamic Republic of)

Contacts

Public Contact?Abolfazl Abdollahpoor

Semnan University of Medical Sciences

abolfazlabdollahpoor@semums.ac.ir+98 23 31420

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026