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Effect of oral immunotherapy in improving Sensitivity in Patients with cow's milk Allergy

Effect of oral immunotherapy with cows milk in desensitizaition and induce tolerance in patients with cows milk allergy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015041621793N1
Enrollment
14
Registered
2015-06-15
Start date
2015-03-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Food allergies. Anaphylactic shock following adverse reactions Food

Interventions

In this study,A certain amount of milk are given to patients under medical supervision and a half hours to be considered.the desensitization beginning with 0.1mL of cow's milk, and increasing the dosa

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 14 Years

Inclusion criteria

Inclusion criteria: inclusion criteria:patients above 3 years old with IgE mediated cow's milk allergy which confirm challenge test exclusion criteria:lack of parental and patient consent,non IgE mediated allergy to cows milk and uncontrolled severe asthma.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Create tolerance to cow's milk. Timepoint: One year after the end of intervention. Method of measurement: clinical signs and open food challenge test.;Desensitization to cow's milk. Timepoint: 6 months after starting intervention. Method of measurement: Based on clinical signs.

Secondary

MeasureTime frame
Changes in the level of specific IgE. Timepoint: before starting intervention and six months after the end of intervention. Method of measurement: RIDA test.;Changes in skin test before and after desensitization. Timepoint: before starting intervention and 6 months after the end of the intervention. Method of measurement: Skin Prick Test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohsen Ebrahimi

Childrens Medical Center

ebrahimi.m@razi.tums.ac.ir+98 21 6693 3926

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026