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Phenytoin ointment in healing anal fistula after surgery

Comparison between topical phenytoin 1% and placebo locally to reduce postoperative pain and recovery time for patients with perianal fistula after fistulotomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015041314483N4
Enrollment
44
Registered
2016-03-21
Start date
2015-02-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anal fistula. Anal fistula

Interventions

Intervention 1: All patients treated by probing fistula tract in lithotomy position under spinal anesthesia. Then direction is probe guided and fistulotomy done in its length and preserve sphincter mu
Treatment - Drugs
Placebo
All patients treated by probing fistula tract in lithotomy position under spinal anesthesia. Then direction is probe guided and fistulotomy done in its length and preserve sphincter muscles involved i

Sponsors

Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Exclusion criteria included: Long-term use of corticosteroids ;diabetes POORLY CONTROL ;TB patients; people with Coron disease; people with underlying malignancy;patients who have had radiation; patients with a history cemotherapy less than 2 weeks; allergy to phenytoin. Inclusion criteria: all patients with anal fistula.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Wound healing. Timepoint: 2,4,6 weeks after surgery. Method of measurement: physical exam.;Fecal and gas incontinency. Timepoint: 2,4,6 weeks after surgery. Method of measurement: wexner questioner.;Post operative pain. Timepoint: 2,4,6 weeks after surgery. Method of measurement: SELFE RELATED ON A VISUAL ANALOG SCALE.

Secondary

MeasureTime frame
Anal pruritus. Timepoint: 2,4,6 weeks after surgery. Method of measurement: 5-D Pruritus Scale.;Wound secretion. Timepoint: 2,4,6 weeks after surgery. Method of measurement: physical exam.;Pain during defecation. Timepoint: 2,4,6 weeks after surgery. Method of measurement: SELFE RELATED ON A VISUAL ANALOG SCALE.;Post operative complications. Timepoint: 2,4,6 weeks after surgery. Method of measurement: physical exam.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026