CABG with CPB. Other complications following infusion, transfusion and therapeutic injection
Conditions
Interventions
Intervention 1: Intervention 2: 200 micro grams of distilled water (placebo) received. We measured by CK-MB, Troponin before the induction of anesthesia, as separate from the pump, 24 hours and 48 ho
Placebo
Treatment - Drugs
Intervention 2: 200 micro grams of distilled water (placebo) received. We measured by CK-MB, Troponin before the induction of anesthesia, as separate from the pump, 24 hours and 48 hours after surger
Intervention1: 200 µg Selenium injected( Bio Sean American.co).We measured CK-MB, TRP before induction, once separated from the pump, 24 hours and 48 hours after surgery,
Sponsors
Vice chancellor for research of Guilan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age 30-65 years old; ASA class 2-3 with 3 vessels occlusion and EF>40-45% and normal preoperative level of selenium(for men: 29-107µg/l and for women: 27-150µg/l) Exclusion criteria: emergency surgery; EF<40%; combined CABG and valve surgeries.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Thyroperoxidase (TPO). Timepoint: Before induction, immediately after CPB, 24 and 48 hours after surgery. Method of measurement: IU/mL-serum.;Creatine phosphokinase. Timepoint: Before induction, immediately after CPB, 24 and 48 hours after surgery. Method of measurement: IU/m-Lserum. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAbbas Sedighinejad
Guilan University of Medical Sciences
Outcome results
None listed