the effect of progesterone in the prevention of preterm delivery

Comparison of the Effects of Vaginal Progesterone (Cyclogest) and Intramuscular Progesterone (Hydroxyprogesterone Caproate) in the Prevention of Preterm Labor

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015040921670N1

Enrollment

Registered

2015-05-05

Start date

2012-11-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complications of labour and delivery. Preterm spontaneous labour with preterm delivery

Interventions

Intervention 1: vaginal progesterone. Intervention 2: intramuscular progesterone.

Treatment - Drugs

vaginal progesterone

intramuscular progesterone

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Inclusion criteria: History of preterm delivery; cervix length of <25 mm at gestational age of 16-20 weeks Exclusion criteria: Multiple pregnancy; severe liver disease; hypertension; diabetes; cardiovascular disease; thromboembolic disorder; seizures; sensitivity to hormonal therapy

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Mean delivery time. Timepoint: The end of intervention. Method of measurement: delivery tima in week.	—

Secondary

Measure	Time frame
Drug side effects. Timepoint: During intervention. Method of measurement: Drug side effects records.;Infant outcomes. Timepoint: End of intervention. Method of measurement: Infant outcomes records.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElham Bahrami

Shahid Sadoughi Universit of Medical Sciences

bahrami-hmrc@ssu.ac.irdr.bahramie7531@gmail.com+98 35 3822 4200

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Mar 8, 2026