Effect of IV Dextrose on postoperative nausea and vomiting after laparoscopic cholecystectomy

Effect of IV dextrose 5% on incidence of postoperative nausea and vomiting after laparoscopic cholecystectomy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201504086803N9

Enrollment

132

Registered

2015-05-27

Start date

2014-05-31

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative nausea and vomiting after laparoscopic cholecystectomy. Vomiting following gastrointestinal surgery

Interventions

Intervention 1: infusion of 500cc solution containing 5% dextrose in Ringer Lactate whithin 30 minutes before induction of anesthesia. Intervention 2: infusion of 500cc solution containing Ringer La

Treatment - Drugs

Placebo

infusion of 500cc solution containing 5% dextrose in Ringer Lactate whithin 30 minutes before induction of anesthesia

infusion of 500cc solution containing Ringer Lactate whithin 30 minutes and before induction of anesthesia

Eligibility

Sex/Gender

Female

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria included: (1) the desire to participate in the study, and informed consent(2) planned laparoscopic cholecystectomy surgery (3) age between 18-65 years. Exclusion criteria included: (1) At any time based on the patient's unwillingness to continue participating in study (2) Systemic hypertension (blood pressure above the 140/90 mm-Hg in two or more measurements(3) renal failure(4) coagulopathy (5)chronic heart failure, (6)liver failure(7) Diabetes mellitus (fasting morning glucose levels over 100 mg / dl)(8) previous history of severe nausea and vomiting after surgery (9)pregnancy(10) surgery prolonged more than 2 hours.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Incidence of nausea and vomiting. Timepoint: immediately and at 30, 60, 90, 120 after recovery and at 6, 12, 24 hours after being discharged from the recovery. Method of measurement: yes/no and Record in Questionnaire.	—

Secondary

Measure	Time frame
Intensity of nausea and vomiting. Timepoint: immediately and at 30, 60, 90, 120 after recovery and at 6, 12, 24 hours after being discharged from the recovery. Method of measurement: VRS(visual rating scale) and Record in Questionnaire.;Use of antiemetics. Timepoint: during 24 hours after surgery. Method of measurement: mg(miligram) and record in questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAbolfazl Firouzian MD

Mazandaran University of Medical Sciences

A.firouzian@mazums.ac.ir; Ab.firouzian@gmail.com+98 11 3337 5038

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026