Infertility. Relative infertility
Conditions
Interventions
Intervention 1: Administerution of cetrotide as gnrh antagonist with dose of 250my per night on cycle day 2 up to 7 days. Intervention 2: Standard gnrh antagonist protocol with estradiol priming.
Treatment - Drugs
Administerution of cetrotide as gnrh antagonist with dose of 250my per night on cycle day 2 up to 7 days
Standard gnrh antagonist protocol with estradiol priming
Sponsors
Vice Chancellor for research of Shiraz University of Medical sciences-shiraz- Iran
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Inclusion criteria: In fertile patient with Age =40 ? history of poor response to controlled ovarian hyper stimulation (3 or less follicle retrieved) ? abnormal ovarian reserve test exclusion criteria: severe male factor infertility ? uterine myoma ? uterine anomaly ? hydrosalpinx
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of patients who met the criteria to proceed to oocyte retrieval. Timepoint: On triggering day with hcg. Method of measurement: Numerical for dominant follicle –oocyte retrieval and mature oocyte retrieval.;Total number of dominant follicle on day of triggering with HCG=13mm. Timepoint: On triggering day with hcg. Method of measurement: Numerical for dominant follicle –oocyte retrieval and mature oocyte retrieval.;Number of retried oocyte. Timepoint: On day of oocyte retrieval. Method of measurement: Numerical for dominant follicle –oocyte retrieval and mature oocyte retrieval. | — |
Secondary
| Measure | Time frame |
|---|---|
| Implantation rate. Timepoint: 1/3 weeks after transfer. Method of measurement: In percentage.;Clinical pregnancy rate. Timepoint: 4/6 weeks after emberyo transfer. Method of measurement: in percentage. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Maryam Azizi
Shiraz University of Medical Sciences
Outcome results
None listed