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Comparison extra amniotic salin infusion and vaginal isoniazide for cervical ripening before induction and labour duration in term and post term pregnancy

Comparison extra amniotic salin infusion and vaginal isoniazide for cervical ripening before induction and labour duration in term and post term pregnancy

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015040721506N2
Enrollment
150
Registered
2015-04-28
Start date
2015-01-02
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy. Normal pregnancy

Interventions

Intervention 1: In another group folly catheter is applied in cervix extra amniotic which bublle filled with 40 mili litre strilewater. Intervention 2: In one group vaginal isoniyazide is applied 900
Treatment - Drugs
In another group folly catheter is applied in cervix extra amniotic which bublle filled with 40 mili litre strilewater
In one group vaginal isoniyazide is applied 900 mg tablets every 4 hours for 3 doses.

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
17 Years to 43 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1- single tone pregnancy 2- bishop score 5 Kg. 2- not reassuring NST. 3- PROM 4-AFI<5 Cm. 5- history of kidney and liver diseases. 6-history of Cesarian section. 7- low lying placenta. 8- any contraindication of isoniazide such as vomiting, nausea, visual defect, vertigo. 9- no cephalic presentation. 10- unexplained vaginal bleeding. 11- labor phase. 12- organic disease. 12- grand multiparity

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Bishap score. Timepoint: Before intervetion and before induction. Method of measurement: Clinical examination.

Secondary

MeasureTime frame
Interval intervention until active phase. Timepoint: Start of intervention till delivery. Method of measurement: Minutes.;Interval between intervention till labour. Timepoint: Start of intervention till delivery. Method of measurement: Minutes.;Time intrval between intervetion till indoction of labour. Timepoint: start of intervention. Method of measurement: minute.;Compliation vomating and nausia and icter and vertigo. Timepoint: Start of intervention till delivery. Method of measurement: Examination and question.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSamira Saadatjoo

Iran University of Medical Sciences

saadat6359@gmail.com+98 21 5553 2277

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026