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Effect of melatonin and vitamin E on working shift nurses’ sleep in ValiAsr Hospital located in Arak

Investigation Effect of melatonin, vitamin E administration on EEG and sleep quality in shift worker Nurses

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015040621626N1
Enrollment
90
Registered
2017-04-21
Start date
2015-04-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sleep disorders. Sleep disorders

Interventions

Intervention 1: Intervention of the first group: receiving a tablet of melatonin 3 mg orally every night for two months, except for working night shifts. Intervention 2: Intervention of the second gro
Treatment - Drugs
Intervention of the first group: receiving a tablet of melatonin 3 mg orally every night for two months, except for working night shifts
Intervention of the second group: receiving a tablet of vitamin E/ 200 Units, orally every day for two months
Intervention of the third group: receiving a tablet of melatonin 3 mg orally every night for two months, except for working night shifts and a tablet of vitamin E/ 200 Units, orally every day for two
Control group: No intervention and measuring outcome variables

Sponsors

Research and Technology Vice Chancellor, Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
22 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: to have at least one year of work experience? six night shifts per month? no second job? no history of sleep problems? no special underlying disease such as gland diseases and thyroid? no use of certain medications such as such as benzodiazepines and anticonvulsants, maximum age of 40 years. Exclusion criteria: Intolerance of melatonin or vitamin E?recent history of melatonin or vitamin E for any other reason? a history of intolerance of melatonin or Vitamin E’s oral use? diagnosis of chronic systemic diseases (other than diabetes and hypertension)? and autoimmune disorders? infections? lack of regular drug use within two months of prescribed drugs? lack of consent to participate in the study? the nurses participated in the study who can’t be reachable for the intervention or follow-up were excluded.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Sleep quality. Timepoint: Befor intervention and 2 month after start of intervention. Method of measurement: TPR and weight.PSQI.;EEG waves. Timepoint: Befor intervention and 2 month after start of intervention. Method of measurement: Electroencephalogram.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohsen Ebrahimi Monfared

Arak University of Medical Sciences

info@arakmu.ac.ir+98 86 3313 6055

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026