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The effect of dextrose infusion on postoperative nausea and vomiting

The effect of preoperative dextrose infusion on postoperative nausea and vomiting

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015032721544N1
Enrollment
298
Registered
2015-06-21
Start date
2015-06-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Nausea and Vomiting. Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

Interventions

Intervention 1: In the study group (n=150) is infused 10 ml/kg/h Ringer’s solution with 100 mL/h dextrose 10% during surgery. Intervention 2: In the placebo group (n=150) is infused of 10 ml/kg/h Ring
Prevention
Placebo
In the study group (n=150) is infused 10 ml/kg/h Ringer’s solution with 100 mL/h dextrose 10% during surgery.
In the placebo group (n=150) is infused of 10 ml/kg/h Ringer’s solution alone in placebo during surgery.

Sponsors

Vice chancellor for research, Shahroud University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: ASA class 1; both sexes; aged 18 to 40 years; Open surgeries that are identical in terms of time and type of anesthesia. Exclusion criteria: diabetics; history of systemic disease (cardiovascular, respiratory, renal ,…); history of nausea and vomiting.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Intensity of Postoperative Nausea and Vomiting. Timepoint: 0 (while the patient is awake), 30, 60, 120 minute and 4 hours after the surgery. Method of measurement: Questionnaire- Visual Analog Scale.

Secondary

MeasureTime frame
Total dose antiemetic drug. Timepoint: Recovery within 24 hours after surgery. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactJavad Nourian MD

Imam Hossein Hospital, Shahroud University of Medical Sciences, Shahroud, Iran

javadnourian@shmu.ac.ir+98 27 3334 2001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026