The evaluation of using Acellular Dermal Matrix Allograft (CenoDerm) together with plasma rich in growth factor in gingival augmentation

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201503261760N38

Enrollment

Registered

2015-04-28

Start date

2014-10-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Lack of attached gingival. Condition 2: Healing. Other disorders of gingiva and edentulous alveolar ridge Superficial injury of lip and oral cavity

Interventions

Intervention 1: Intervention Group:The only difference will be in rehydration liquid that is PRGF in the intervention group. Intervention 2: Control Group: The thickness of Cenoderm® will be 1.5 mm.

Treatment - Drugs

Intervention Group:The only difference will be in rehydration liquid that is PRGF in the intervention group

Control Group: The thickness of Cenoderm® will be 1.5 mm. In the control group of normal saline rehydration will be done.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria: At least 18 years of age; The sound system; The plaque before transplantation, 25% or less; Deficient gingival bilaterally Exclusion criteria: Smoking; Pregnancy; There occlusal trauma; Surgical procedures were performed in the desired area in the last 12 months; Oral mucosal disease; There are more than 3 mm region of the envelope with the link; Periapical lesion; Beyond tooth mobility grade 1; Affecting periodontal medication (eg, phenytoin, oral contraceptives, estrogen and progesterone compounds, of activities and cyclosporine)

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Width of keratinized gingival. Timepoint: Before surgery and one and three months after surgery. Method of measurement: Probe Williams with compass and caliper as well as the roll test.;Healing index. Timepoint: Day three, seven, ten and fourteen, and one month and three months after surgery. Method of measurement: Landry Healing index.	—

Secondary

Measure	Time frame
Pain Index. Timepoint: Before surgery and one and three months after surgery. Method of measurement: Visual Analogue Scale.;Gingiva thickness. Timepoint: Before surgery and one and three months after surgery. Method of measurement: Williams probe.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Pasha Ghahari

Dental colleges of Babol

pashaghahari1366@gmail.com+98 11 3229 1408

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026