Plaque Psoriasis. Psoriasis vulgaris
Conditions
Interventions
Intervention 1: Herbal ointment containing 5% Hypericum perfuratum extract in Vaseline base was used on lesions of one side of the body twice daily. Intervention 2: Placebo ointment in Vaseline base
Treatment - Drugs
Placebo
Herbal ointment containing 5% Hypericum perfuratum extract in Vaseline base was used on lesions of one side of the body twice daily.
Placebo ointment in Vaseline base was used on the lesions of the other side of the body twice daily.
Sponsors
Islamic Azad University, Pharmaceutical Sciences Branch
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients with the age between 18 to 50 years old; diagnosis of mild to moderate plaque type psoriasis on both sides of the body; not being under medical treatment for the past two months. Exclusion criteria: pregnancy; lactation; suffering from a major illness (such as cardiovascular disease, acute renal or liver disease, cancer or active malignancy); not having plaque psoriasis on both sides of the body.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Erythema, Thickness, Scaling. Timepoint: At the end of week 4. Method of measurement: Modified psoriasis area severity index (PASI) scores.;Tissue TNFa Level. Timepoint: At the end of Week 4. Method of measurement: Mouse anti-human TNFa (28401.111) monoclonal antibody. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects. Timepoint: At the end of week 4. Method of measurement: Questionnaire, Photography, Scoring. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Farshad Hashemian
Islamic Azad University, Pharmaceutical Sciences Branch, Faculty of Pharmacy
Outcome results
None listed